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MTHFR

 

MTHFR (methylenetetrahydrofolate reductase) is a gene that sometimes has a defect that deactivates the MTHFR enzyme,  which when working properly converts Folate and Folic Acid into active forms that the body can use.  The current theory is that a  genetic defect reduces the effectiveness of that important conversion.

Symptoms of MTHFR

Some possible symptoms of MTHFR include:

  • Dementia
  • Fibromyalgia
  • Anxiety and depression
  • Migraines
  • Miscarriage and pregnancies with neural tube defects
  •  Pain and inflammation
  • Chronic fatigue
  • Chemical sensitivity syndrome
  • detoxification inefficiencies
  • Neurotransmitters, (dopamine, serotonin, melatonin) deficiencies

MTHFR mutation is diagnosed through a simple test

Testing with a simple blood test should be first step.   

Additional tests that I recommend include the following:

  • Hair analysis.  
  • Viral blood panel.
  • Micronutrient blood test.

When an MTHFR mutation comes back positive for an MTHFR gene mutation, most frequently it is either C6777T, A1298C or both.

MTHFR defects are numerous, diverse, and correlate with an overburdened and possibly toxic liver and lack of key nutrients like Vitamin B12.  An interesting and helpful book written on methylation defect and MTHFR is called “Dirty Genes” by Dr. Ben Lynch.  Perhaps a more accurate title could have been “Dirty Blood”.  A liver that is overwhelmed with toxins and clogged by poisonous chemical debris and viral neurotoxins, gives the impression that the genes are mutated.  Testing then show elevated inflammation markers like high homocysteine and the presence of unacceptably high levels of toxins both chemical and viral. It’s a mistake in my opinion to jump to the conclusion that your genes and DNA are irretrievably damaged.

 MTHFR Diagnosis

If you do have a genetic defect, help is available. Some health and lifestyle changes to consider are:

  • Avoid Folic Acid, gluten, wheat and sugar.
  • Consume dark, leafy green vegetables.
  • Exercise regularly 3 – 5 times a week.
  • Optimize your diet with organic foods, fermented food and unprocessed foods.
  • Use environmentally friendly cleaning products.

Under the supervision of a holistic medical professional supplementation and specific detox regimens are widely available.  This practitioner should be familiar with MTHFR defects and have a background  including nutritional biochemistry and genetics. 

Detox and supplement regimens should start slowly, at a low dosage and under a doctor’s orders.  This is to minimize the overload of kill off and/or toxin release on the detox organs. This will improve your outcomes and for your safety and optimal wellness.

Dr. Cushing D.C.,D.Ch.,C.N.C.,F.S.A.C

 

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