Charlotte NC 704-776-4185 or 704-246-8244[email protected]

Pyroluria – Connected to ADD/ADHD, OCD, Bipolar

Pyroluria is a condition wherein your body formulates and excretes the enzyme Hydroxyhemopyrrolin-2-one (HPL)in excess. If your body forms this molecule in excess the molecules may attach themselves to nutrients such as zinc and vitamin B6, causing them to be excreted in urine before they are absorbed properly by your body.

Pyroluria is connected to these syndromes:

  • OCD
  • Bipolar
  • Depression
  • Autism
  • Low Motivation
  • Mood imbalances
  • Brain based behavioral issues
  • Schizophrenia
  • Anger issues
  • Anxiety
  • Acute shyness
  • Fear of public speaking
  • Sensitivity to light, sound & food textures
  • Substance Abuse
  • MS
  • Parkinson’s
  • Crime and delinquency.

Percentages for syndromes above that suffer with Pyroluria:

  • 50% of those with autism.
  • 40% of alcoholics.
  • 70% of schizophrenics.
  • 70% of persons with depression/bipolar.
  • 30% of persons struggling with ADD/ADHD.
  • 80% of chronic Lyme disease patients.

Pyroluria is not limited to these conditions.  Up to 10% of the population may unknowingly have this metabolic condition.  These are life long symptoms that may worsen with age and increased stress.  Unfortunately, reaching for anti-depressants and/or anti-anxiety drugs often exacerbates the condition.

Protracted Stress and its Connection with Pyroluria.

As we age, our bodies way of dealing with day to day stressors that affect our moods and ability to cope becomes increasingly difficult.  The severity of moods and their duration can be difficult obstacles to overcome.  This often leaves a patient fatigued and prone to viral syndromes like chronic fatigue syndrome. 

Patients with these symptoms usually visit a doctor to get a prescription for a mood enhancing drug to get relief.  This treatment temporarily reduces some symptoms, or it may cause a completely new set of side effects that make the original issue worse.  This type of therapy does not address the underlying issues or bring back energy levels or stop patients from getting sick with viral/bacterial infection. 

We find that patients in their younger years have Pyroluria, however have not have shown any symptoms until later in life.  This is due to either acute or protracted stressors that triggering the condition.

Abnormalities found in patients with Pyroluria

The vast majority of all these syndromes have at their root, some of the following abnormalities:

  • Elevated urine pyrroles
  • Abnormal copper/zinc ratios
  • Toxic metal overload
  • Low blood copper and or high tissue copper
  • Thyroid and/ or adrenal hormonal imbalances
  • Low blood histamine levels
  • Poor methylation
  • Food/chemical/inhalant allergies

What testing is available for Pyroluria?

A  simple and inexpensive test that uses blood and urine is performed, to find out whether a patient has Pyroluria.  This test is available through some of the more holistic doctors who have been through the specialized training in diagnosing and treating this condition. 

As an experienced practitioner, Dr. Cushing also performs a simple in office test to see if a patient is likely to have Pyroluria before  proceeding with a lab test to confirm the diagnosis.  As many conditions have overlapping symptoms, the lay patient would be unlikely  to be able to  determine whether the test is necessary.

How is this treated?

For recovery or relief and to correct the lab based findings for a Pyroluria patient, a nutrient program will be customized to suit a patients individual chemistry.  This can be done at home with the supervision of an experienced Pyroluria doctor who can guide the patient back to optimum health.

Dr. A. I. Cushing D.C.,D.Ch.,C.N.C.,F.S.A.C.

Author Info

Arthur Cushing